Narcotine and Hydrastine. A Study of the Mechanism of their Conversion into Narceine, Methylhydrasteine and their Derivatives1

CR Addinall, RT Major

Index: Addinall; Major Journal of the American Chemical Society, 1933 , vol. 55, p. 2153,2161

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Citation Number: 7

Abstract

Iodine in liquid ammoriia has been found to be an effective reagent for the direct iodination of monosubstituted acetylenes. Phenyl, tolyl and vinyl acetylenes react with iodine in ammonia at-34'giving almost theoretical yields of the corresponding iodoacetylene. Ethyl, butyl, amyl and heptyl acetylenes react slowly with ammonia solutions of iodine at-34". At 25" 1545% yields of the iodoacetylenes are obtained.