Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor

AA Mazurov, DC Kombo, S Akireddy, S Murthy…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 13 p. 3927 - 3934

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Citation Number: 8

Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 23, Issue 13, 1 July 2013, Pages 3927–3934. ... 4 Peripheral and central adverse effects of the partial α4β2 nAChR agonist 3, a smoking cessation medicine, may also be attributed to suboptimal subtype selectivity. 5. ...