Preparations of Anthraquinone and Naphthoquinone Derivatives and Their Cytotoxic Effects

…, R Saito, T Kubo, D Kon, Y Hirano, S Saito

Index: Cui, Xing-Ri; Saito, Ryota; Kubo, Takatsugu; Kon, Daijiro; Hirano, Yuich; Saito, Setsuo Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 3 p. 302 - 314

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Citation Number: 2

Abstract

Chrysophanol and 1, 8-di-O-hexylchrysophanol derivatives having nucleic acid bases at position 5 were synthesized. Furthermore, derivatives of menadione substituted at position 11 (type A naphthoquinone derivatives) or methylmenadione substituted at position 7 (type B naphthoquinone derivatives) modified with nucleic acid bases, amines and thiocyano, selenocyano or thioacetyl groups were synthesized. The cytotoxic effects of these ...