Tetrahedron

Thiénopyrimidines—II: Etude de la thiéno [3.2-d] pyrimidine et de quelques dérivés

M Robba, JM Lecomte, MC De Sévricourt

Index: Robba,M. et al. Tetrahedron, 1971 , vol. 27, p. 487 - 499

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Citation Number: 22

Abstract

The nucleophilic substitution of 4-chloro thieno [3.2-d] pyrimidine has been studied. The synthesis of thieno [3.2-d] pyrimidine was made via catalytic reduction of the 4-chloro thieno [3.2-d] pyrimidine and by oxidation of the 4-hydrazino thieno [3.2-d] pyrimidine. Electrophilic substitution of thieno [3.2-d] pyrimidine yielded derivatives bearing substituents at C-7. NMR spectral data are given for various thieno [3.2-d] pyrimidines, and the structures assigned ...