Synlett

One-Pot, Three-Component Copper-Catalysed 'Click'Triazole Synthesis Utilising the Inexpensive, Shelf-Stable Diazotransfer Reagent Imidazole-1-sulfonyl Azide …

…, R Jewell, MWD Perry, MJ Stocks, JP Stonehouse

Index: Smith, Neal M.; Greaves, Michelle J.; Jewell, Robert; Perry, Matthew W. D.; Stocks, Michael J.; Stonehouse, Jeffrey P. Synlett, 2009 , # 9 p. 1391 - 1394

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Citation Number: 18

Abstract

Abstract A practical and efficient one-pot procedure for the regioselective synthesis of functionalised 1, 4-disubstituted 1, 2, 3-triazoles from primary amines and terminal acetylenes has been established utilising the inexpensive, shelf-stable diazotransfer reagent imidazole-1-sulfonyl azide hydrochloride.