The Journal of Organic Chemistry

Studies toward thiostrepton antibiotics: assembly of the central pyridine-thiazole cluster of micrococcins

MA Ciufolini, YC Shen

Index: Ciufolini, Marco A.; Shen, Yong Chun Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3804 - 3805

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Citation Number: 54

Abstract

Micrococcin P1, 1, 1 is a member of the thiostrepton family of antibiotics, 2 and it is a potent inhibitor of protein synthesis, seemingly as a result of interaction with ribosomal RNA. 3 Thiostrepton itself 4 and other members of the the same family5 have been found to ...