Total synthesis of paracentrone, C 31-allenic apo-carotenoid

…, T Shimofusa, N Furuichi, S Katsumura

Index: Murakami, Yusuke; Nakano, Masayuki; Shimofusa, Takuya; Furuichi, Noriyuki; Katsumura, Shigeo Organic and Biomolecular Chemistry, 2005 , vol. 3, # 8 p. 1372 - 1374

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Citation Number: 23

Abstract

The stereocontrolled total synthesis of a C31-allenic apo-carotenoid, paracentrone, was achieved by the convergent C20+ C11= C31 strategy. The key elements of our synthesis were the Pd-catalyzed cross-coupling to stereoselectively construct the conjugated polyene backbone skeleton and the designed geometrical isomerization at the central double bond of the conjugated polyene chain. In addition, the terminal oxygenated cyclohexane ring ...