Synthesis of Novel Thiazolyl??Pyrimidines and Their Anticancer Activity in Vitro

HB Shi, HB Li, KQ Lu, XR Zhu, WX Hu…

Index: Shi, Hai-Bo; Li, Hai-Bo; Lu, Kong-Qin; Zhu, Xia-Re; Hu, Wei-Xiao; Pei, Wen Archiv der Pharmazie, 2011 , vol. 344, # 10 p. 675 - 683

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Citation Number: 3

Abstract

Abstract A series of novel compounds 7–43 were prepared via the condensation of enaminones 4a–h and the guanidines carbonate 6a–f. The structures of these newly synthesized compounds were confirmed by 1 H-NMR, MS, EA and IR. All the compounds