Cu-catalyzed couplings of aryl iodonium salts with sodium trifluoromethanesulfinate

SC Cullen, S Shekhar, NK Nere

Index: Cullen, Steven C.; Shekhar, Shashank; Nere, Nandkishor K. Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12194 - 12201

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Citation Number: 31

Abstract

A convenient method for the preparation of aryl trifluoromethylsulfones from the reactions of diaryliodonium salts with sodium trifluoromethanesulfinate in the presence of copper catalysts is described. Cuprous oxide in DMF was found to be the optimal catalyst for the reaction. The reaction conditions are tolerant of various functional groups as well as of various counteranions of the iodonium salt. The synthetic utility of the process is ...