Tetrahedron letters

Electrophilic asymmetric syntheses of α-hydroxy carboxylic acids

JW Ludwig, M Newcomb, DE Bergbreiter

Index: Ludwig, Jerry W.; Newcomb, Martin; Bergbreiter, David E. Tetrahedron Letters, 1986 , vol. 27, # 24 p. 2731 - 2734

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Citation Number: 22

Abstract

Asymmetric syntheses of α-hydroxy carboxamides by alkylation of enolates formed from 2–8 are described (2; R = -CH 3 , X= -H: 3; R = -H, X = -OCH 3 : 4; R = -CH 3 , X = -OCH 3 : 5; 2 R = -CH 3 , 1 R = -C(CH 3 ) 3 : 6; 1 R = -Si(CH 3 ) 2 C(CH 3 ) 3 , 2 R = -H). ... Camille and Henry Dreyfus Teacher-Scholar, 1980–1985. ... Cookies are used by this site. To decline or learn more, visit our Cookies page.