Biocatalytic Enantioselective Oxidative C C Coupling by Aerobic C H Activation

…, WD Lienhart, K Durchschein, A Winkler…

Index: Schrittwieser, Joerg H.; Resch, Verena; Sattler, Johann H.; Lienhart, Wolf-Dieter; Durchschein, Katharina; Winkler, Andreas; Gruber, Karl; MacHeroux, Peter; Kroutil, Wolfgang Angewandte Chemie - International Edition, 2011 , vol. 50, # 5 p. 1068 - 1071

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Citation Number: 58

Abstract

Reactions that form carbon–carbon bonds are the basis for organic chemistry, setting up the carbon framework of organic molecules. In particular, the formation of CÀC bonds by organo- or metal-catalyzed activation of CÀH bonds [1] has recently obtained increased attention.[2] However, to the best of our knowledge, no biocatalytic oxidative CÀC bondforming reaction has yet been exploited for synthetic purposes. To date, biocatalysis only offers a limited ...