e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor

DW Kung, SB Coffey, RM Jones, S Cabral…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 13 p. 4281 - 4287

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Citation Number: 16

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Likely, this results from advances in the ability to rapidly screen this target and to identify novel chemical matter. ...

tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate Structure

tert-Butyl 2,7-...

~%

2-benzyl-2,7-diazaspiro[3.5]nonane Structure

2-benzyl-2,7-di...

tert-butyl 2-benzyl-2,7-diazaspiro[3.5]nonane-7-carboxylate Structure

tert-butyl 2-be...

~%

2-benzyl-2,7-diazaspiro[3.5]nonane Structure

2-benzyl-2,7-di...

Benzaldehyde Structure

~%

2-benzyl-2,7-diazaspiro[3.5]nonane Structure

2-benzyl-2,7-di...

tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate Structure

tert-Butyl 2,7-...

Benzaldehyde Structure

~%

tert-butyl 2-benzyl-2,7-diazaspiro[3.5]nonane-7-carboxylate Structure

tert-butyl 2-be...

Identification of spirocyclic piperidine-azetidine inverse a...

[Kung, Daniel W.; Coffey, Steven B.; Jones, Ryan M.; Cabral, Shawn; Jiao, Wenhua; Fichtner, Michael; Carpino, Philip A.; Rose, Colin R.; Hank, Richard F.; Lopaze, Michael G.; Swartz, Roger; Chen, Hou Tommy; Hendsch, Zachary; Posner, Bruce; Wielis, Christopher F.; Manning, Brian; Dubins, Jeffrey; Stock, Ingrid A.; Varma, Sam; Campbell, Mary; Debartola, Demetria; Kosa-Maines, Rachel; Steyn, Stefanus J.; McClure, Kim F. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4281 - 4287]

Identification of spirocyclic piperidine-azetidine inverse a...

[Kung, Daniel W.; Coffey, Steven B.; Jones, Ryan M.; Cabral, Shawn; Jiao, Wenhua; Fichtner, Michael; Carpino, Philip A.; Rose, Colin R.; Hank, Richard F.; Lopaze, Michael G.; Swartz, Roger; Chen, Hou Tommy; Hendsch, Zachary; Posner, Bruce; Wielis, Christopher F.; Manning, Brian; Dubins, Jeffrey; Stock, Ingrid A.; Varma, Sam; Campbell, Mary; Debartola, Demetria; Kosa-Maines, Rachel; Steyn, Stefanus J.; McClure, Kim F. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4281 - 4287]

Identification of spirocyclic piperidine-azetidine inverse a...

[Kung, Daniel W.; Coffey, Steven B.; Jones, Ryan M.; Cabral, Shawn; Jiao, Wenhua; Fichtner, Michael; Carpino, Philip A.; Rose, Colin R.; Hank, Richard F.; Lopaze, Michael G.; Swartz, Roger; Chen, Hou Tommy; Hendsch, Zachary; Posner, Bruce; Wielis, Christopher F.; Manning, Brian; Dubins, Jeffrey; Stock, Ingrid A.; Varma, Sam; Campbell, Mary; Debartola, Demetria; Kosa-Maines, Rachel; Steyn, Stefanus J.; McClure, Kim F. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4281 - 4287]