Discovery of novel potent and selective dipeptide hepatitis C virus NS3/4A serine protease inhibitors

P Raboisson, TI Lin, H de Kock, S Vendeville…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 18 p. 5095 - 5100

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Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 6 and 14 In this letter, we report on our efforts to design a novel series of NS3/4A protease inhibitors obtained by further truncation of the N-terminal part of previously reported macrocyclic series (eg, BILN 2061, 1). 11. ...