e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
General method for the preparation of N-monosubstituted 3-isothiazole and 3-(1, 2, 5-thiadiazole) amines. Preparation of a new class of 2-substituted 1, 2, 5-thiadiazol …
J Rokach, P Hamel, Y Girard…
Index: Rokach,J. et al. Journal of Organic Chemistry, 1979 , vol. 44, p. 1118 - 1124
J. Rokach,* P. Hamel, Y. Girard, and G. Reader ... Merck Frosst Laboratories, Pointe Claire/Dorual, Quebec H9R 4P8, Canada Received July 25, 1978 ... The preparations of N-monosubstituted 3-isothiazole and 3-( 1,2,5-thiadiazol)amines and the corresponding 2- substituted compounds are described. A general method for the preparation of the previously unknown 2-substitut- ed 1,2,5-thiadiazo1-3(2H)-ones is presented. Mechanistic evidence is presented for the ...
