Tetrahedron

A novel one-pot synthesis of substituted 1, 4-dihydropyridines and its application to total synthesis of the alkaloid isoalamarine from AlangiumlamarckiiThw.

US Chowdhury

Index: Chowdhury, Uday Sankar Tetrahedron, 1990 , vol. 46, # 23 p. 7893 - 7900

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Citation Number: 8

Abstract

A novel method for one pot synthesis of unsymmetrical 3, 5-disubstituted and 3, 4, 5,- trisubstituted 1, 4-dihydropyridines has been developed. The first total synthesis of the alkaloid isoalamarine (1), involving 3-acetyl-5-carbomethoxy pyridine has been