Synthesis and structure-activity relationships of benzo [b] thienylallylamine antimycotics

P Nussbaumer, G Petranyi, A Stuetz

Index: Journal of Medicinal Chemistry, , vol. 34, # 1 p. 65 - 73

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Citation Number: 64

Abstract

... new synthetic strategies, has led to the discovery of ter- binafine (SF 86-327, Lamisil, 21, the first pharmaceutical agent to contain an (E)-1,3-enyne structural element.2 Terbinafine exhibits considerably higher activity than the ... 66 Journal of Medicinal Chemistry, 1991, Vol. ...