Synthesis of all??trans??beta??carotene retinoids and derivatives labelled with 14C

…, P Auzeloux, JC Maurizis, V Braesco…

Index: Azim, El-Mostafa; Auzeloux, Philippe; Maurizis, Jean-Claude; Braesco, Veronique; Grolier, Pascal; Veyre, Annie; Madelmont, Jean-Claude Journal of Labelled Compounds and Radiopharmaceuticals, 1996 , vol. 38, # 5 p. 441 - 451

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Citation Number: 9

Abstract

Abstract In this paper we report the synthesis of all-trans Retinoic acid, Retinal, Retinol specifically labelled with 14 C at position 7 and all-trans Beta-carotene labelled at positions 7 and 7′, with more than 98% radiochemical purity. All products were obtained with about 15% overall yield from 14 C sodium cyanide.