e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Bornane sultam-directed asymmetric synthesis of crystalline, enantiomerically pure syn aldols

W Oppolzer, J Blagg, I Rodriguez…

Index: Journal of the American Chemical Society, , vol. 112, # 7 p. 2767 - 2772

Full Text: HTML

Citation Number: 237

Abstract

... This work was supported by the National Institutes of Health (GM-30528) and the National Science Foundation (CHE-8721312) and a Merck Sharp and Dohme sponsored 1988-1 989 ACS Division of Organic Chemistry Fel- lowship ... 0 1990 American Chemical Society ... Soc., Vol. ...

N-((2R,3S)-3-hydroxy-2-methylbutanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~%

n-propionyl-(2r)-bornane- 10,2-sultam Structure

n-propionyl-(2r...

N-((2R,3S)-3-hydroxy-2-methylbutanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~91%

N/A Structure

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

N/A Structure

~94%

(2S,3S)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpentan-1-ol Structure

(2S,3S)-3-[tert...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

N-((2R,3S)-3-hydroxy-2,4-dimethylpentanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~95%

N/A Structure

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

N/A Structure

~88%

(1R*,2S*)-2-methyl-1-phenylpropane-1,3-diol Structure

(1R*,2S*)-2-met...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

N-((2R,3S)-3-hydroxy-2-methylpentanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~%

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N-((2R,3S)-3-hydroxy-2-methylbutanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~%

methyl (2R,3S)-2-methyl-3-hydroxybutanoate Structure

methyl (2R,3S)-...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N-((2R,3S)-3-hydroxy-2,4-dimethylpentanoyl)bornane-10,2-sultam Structure

N-((2R,3S)-3-hy...

~%

[2R,3S]-(+)-methyl-3-hydroxy-2,4-dimethyl-pentanoate Structure

[2R,3S]-(+)-met...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N-[(2S,3R)-3-hydroxy-2,4-dimethylpentanoyl]bornane-10,2-sultam Structure

N-[(2S,3R)-3-hy...

~%

methyl (2RS,3SR)-3-hydroxy-2,4-dimethylpentanoate Structure

methyl (2RS,3SR...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

N/A Structure

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

(2S,3R)-methyl 2-ethyl-4-methyl-3-hydroxypropanoate Structure

(2S,3R)-methyl ...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

N/A Structure

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

N/A Structure

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

anti-β-hydroxy-α-methylbenzenepropanoic acid methyl ester Structure

anti-β-hydroxy-...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

anti-β-hydroxy-α-methylbenzenepropanoic acid methyl ester Structure

anti-β-hydroxy-...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

methyl 2-ethyl-3-hydroxy-3-phenylpropionate Structure

methyl 2-ethyl-...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

diazomethane Structure

N/A Structure

~%

methyl (2S)-2-[(S)-hydroxy(phenyl)methyl]butanoate Structure

methyl (2S)-2-[...

(2R)-Bornane-10,2-sultam Structure

(2R)-Bornane-10...

Diastereoselective synthesis of the C14–C29 fragment of amph...

[Organic and Biomolecular Chemistry, , vol. 11, # 39 p. 6829 - 6840]

Lithium-initiated imide formation. A simple method for N-acy...

[Journal of Organic Chemistry, , vol. 60, # 7 p. 2271 - 2273]