Enantioselective synthesis of 4-hydroxy-D-pyroglutamic acid derivatives by an asymmetric 1, 3-dipolar cycloaddition

…, J Revuelta, T Tejero, U Chiacchio, A Rescifina…

Index: Merino, Pedro; Revuelta, Julia; Tejero, Tomas; Chiacchio, Ugo; Rescifina, Antonio; Piperno, Anna; Romeo, Giovanni Tetrahedron Asymmetry, 2002 , vol. 13, # 2 p. 167 - 172

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Citation Number: 39

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The 1,3-dipolar cycloaddition of a chiral nitrone derived from glyoxylic acid and protected d-ribosyl hydroxylamine with the acrylamide of Oppolzer's sultam provides a perfectly stereoselective approach to protected (2R,4R)-4-hydroxy-d-pyroglutamic acid. ... Pyroglutamic acids and ...