Claisen Condensation as a Facile Route to an α-Alkoxy-cinnamate: Synthesis of Ethyl (2 S)-2-Ethoxy-3-(4-hydroxyphenyl) propanoate

MT Linderberg, M Moge…

Index: Organic Process Research and Development, , vol. 8, # 6 p. 838 - 845

Full Text: HTML

Citation Number: 24

Abstract

... Organic Process Research & Development. ... While the starting materials for this synthesis were inexpensive, the initial process suffered from several problems. ... A precedent case from the literature 5 shows a procedure for the condensation of ethyl methoxyacetate (3 equiv) and ...