Journal of the American Chemical Society

Studies on Peptides. II. Synthesis and Physiological Properties of D-Histidyl-D-phenylalanyl-D-arginyl-D-tryptophylglycine, an Optical Antipode of an Active Fragment …

H Yajima, K Kubo

Index: Yajima,H.; Kubo,K. Journal of the American Chemical Society, 1965 , vol. 87, p. 2039 - 2044

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Citation Number: 34

Abstract

It is a well-documented phenomenon that heating pituitary extracts in an alkaline solution causes prolongation of melanocyte-stimulating activity as well as potentiation of its action to frog skin in an in vivo~ ystem.~-~ Among the hormones produced by the mammalian pituitary glands, adrenocorticotropic hormone (ACTH) 6 and two types of melanocyte- stimulating hormones5 (MSH), a-MSH and@-MSH, are known to be the main components ...