Bis [[4-(2, 2-dimethyl-1, 3-dioxolyl)] methyl]-carbodiimide (BDDC) and its application to residue-free esterifications, peptide couplings, and dehydrations

FS Gibson, MS Park, H Rapoport

Index: Journal of Organic Chemistry, , vol. 59, # 24 p. 7503 - 7507

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Citation Number: 65

Abstract

... We now report the synthesis and chemistry of bis[[4-(2,2-dimethyl-l,3-diox- olyl) lmethyllcarbodiimide (BDDC, 1) and that of several ... The neutrality of the propanediol isopropylidene ketal side chains allows for enhanced organic solubility, ease of isourea formation, and use. ... J. ...

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Bis [[4-(2, 2-dimethyl-1, 3-dioxolyl)] methyl]-carbodiimide ...

[Gibson, Frank S.; Park, Myung Sook; Rapoport, Henry Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7503 - 7507]

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