Phytochemistry

Biosynthesis of axenomycin d: Incorporation of 13 C-labelled precursors into the menadione chromophore, desoxysugars and the axenolide

V Friese, A Boos, HJ Bauch, E Leistner

Index: Friese, V.; Boos, A.; Bauch, H.-J.; Leistner, E. Phytochemistry (Elsevier), 1993 , vol. 32, # 3 p. 613 - 622

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Citation Number: 8

Abstract

Abstract Experiments on the biosynthesis of the menadione chromophore of axenomycin D in Streptomyces lisandri resulted in the specific incorporation of label from l-[13 C-Me] methionine,[1-13 C] propionate,[2, 3-13 C 2] propionate,[3-13 C] propionate,[U-13 C 3] glycerol and [U-13 C 6] glucose. The data indicate that the menadione chromophore is derived from a metabolite of the shikimate pathway. The mode of incorporation shows, ...