Organic letters

Lipase-catalyzed enantioselective ring opening of unactivated alicyclic-fused β-lactams in an organic solvent

E Forró, F Fülöp

Index: Evans, Chris; McCague, Ray; Roberts, Stanley M.; Sutherland Alan G.; Wisdom, Richard Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 9 p. 2276 - 2277

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Citation Number: 95

Abstract

... Evans et al. ... 17 d, (±)-4, Lipolase, 1, 20, 24, >95, >49. a 0.05 M substrate in diisopropyl ether, 60 °C. b According to GC. ... d Calculated by using an internal standard (hexadecane). e c = 0.5; CHCl 3 . f c = 0.5; H 2 O. g [α] 25 D −19.6 (c 0.25, H 2 O). 17b h c = 0.4; H 2 O. ...