Pursuing this novel direction of research, some ten years ago we developed general methods for the synthesis of previously unknown aza-analogs of styrylquinolines, namely 4- amino-2-styrylquinazolines (I)[15, 16]. These methods were based on the reaction of 2- methyl-4-chloroquinazolines (V), obtained from the anthranilic acids (II) or acetanilides (III) via the 2-methyl-4-quinazolones (IV) with amines, followed by condensation of the ...
