Synthesis

Lipase-mediated resolution of trans-1-azidoindan-2-ol: a new route to optically pure cis-1-aminoindan-2-ol

M Takahashi, K Ogasawara

Index: Takahashi, Michiyasu; Ogasawara, Kunio Synthesis, 1996 , # 8 p. 954 - 958

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Citation Number: 17

Abstract

Optically pure trans-1-azidoindan-2-ol has been prepared in both enantiomeric forms via lipase-mediated kinetic transesterification in organic solvent. A route to optically pure cis-1- aminoindan-2-ol has also been developed by using the optically pure trans-azidoalcohol thus obtained.