Molecules

Synthesis of platinum complexes from N-benzyl-1, 3-propanediamine derivatives, potential antineoplastic agents

…, RN Berg, ET César, E De Castro Antunes Felício…

Index: De Almeida, Mauro Vieira; Fontes, Ana Paula Soares; Berg, Richard Nilton; Cesar, Eloi Teixeira; Felicio, Emanoel De Castro Antunes; De Souza Filho, Jose Dias Molecules, 2002 , vol. 7, # 4 p. 405 - 411

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Citation Number: 6

Abstract

Abstract: This work describes the synthesis of seven new platinum complexes having N- benzyl 1, 3-propanediamine derivatives as ligands. They were prepared by the reaction of K 2 [PtCl 4] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.