Microwave??assisted Synthesis and Bioevaluation of Some Semicarbazones

L Jafri, FL Ansari, M Jamil, S Kalsoom…

Index: Jafri, Laila; Ansari, Farzana L.; Jamil, Maryam; Kalsoom, Saima; Qureishi, Sana; Mirza, Bushra Chemical Biology and Drug Design, 2012 , vol. 79, # 6 p. 950 - 959

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Citation Number: 10

Abstract

In continuation to our efforts in finding potential therapeutic agents, a variety of biologically significant semicarbazones were synthesized by the reaction of different carbonyl compounds with phenyl semicarbazides through microwave irradiation. Initially, 18 semicarbazones were studied for their antimicrobial, antitumor, and antioxidant potential. None of the tested compounds showed any antibacterial activity; however, some ...