Attempts to diketosteroids or on C-ring uiisubstituted compounds. chain groups markedly and affects the ease of introduction of new groups into the side chain. nenes (seven compounds) and 12-ketopregnanes (three compounds) are prepared and their propertics noted. prepare 4-pregne1ie-17a, 21-diol-3, 12, 20-trione by the hecogenin route have not yet been successful.
