Chemical Communications

The in situ oxidation–Wittig reaction of α-hydroxyketones

KA Runcie, RJK Taylor

Index: Runcie, Karen A.; Taylor, Richard J. K. Chemical Communications, 2002 , # 9 p. 974 - 975

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Citation Number: 25

Abstract

In situ oxidation–Wittig methodology has been applied to α-hydroxyketones avoiding the problems normally associated with α-ketoaldehydes; the procedure is practically simple, and in many cases gives high yields of the product γ-ketocrotonates; the procedure has also been successfully utilised with ethyl glycolate and glycolaldehyde dimer.