e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Prenylation of methoxyhydroquinone in aqueous acid solution and an alternative synthesis of precocene II

M Uchiyama, JC Overeem

Index: Uchiyama, M.; Overeem, J. C. Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 11 p. 408 - 410

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Abstract

Abstract The acid-catalyzed condensation of methoxyhydroquinone with 2-methyl-3-buten-2- ol leads to 2-methoxy-5-(3-methyl-2-butenyl) hydroquinone (4) and 2-(1, 1-dimethylallyl)-5- methoxy-hydroquinone (7). Compound 4 can easily be converted into precocene II (1, R

2-methoxy-5-(3-methylbut-2-enyl)benzene-1,4-diol Structure

2-methoxy-5-(3-...

~%

2,5-Cyclohexadiene-1,4-dione,2-methoxy-5-(3-methyl-2-buten-1-yl)- Structure

2,5-Cyclohexadi...

2-Methyl-3-buten-2-ol Structure

2-Methyl-3-bute...

~%

2,5-Cyclohexadiene-1,4-dione,2-methoxy-5-(3-methyl-2-buten-1-yl)- Structure

2,5-Cyclohexadi...

2-methoxyhydroquinone Structure

2-methoxyhydroq...

~%

2,5-Cyclohexadiene-1,4-dione,2-methoxy-5-(3-methyl-2-buten-1-yl)- Structure

2,5-Cyclohexadi...

… of prenylated quinones by the oxidative degradation approa...

[Ballester, Pablo; Capo, Magdalena; Garcias, Xavier; Saa, Jose M. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 328 - 334]

… of prenylated quinones by the oxidative degradation approa...

[Ballester, Pablo; Capo, Magdalena; Garcias, Xavier; Saa, Jose M. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 328 - 334]

… of prenylated quinones by the oxidative degradation approa...

[Ballester, Pablo; Capo, Magdalena; Garcias, Xavier; Saa, Jose M. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 328 - 334]

… of prenylated quinones by the oxidative degradation approa...

[Ballester, Pablo; Capo, Magdalena; Garcias, Xavier; Saa, Jose M. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 328 - 334]

… of prenylated quinones by the oxidative degradation approa...

[Ballester, Pablo; Capo, Magdalena; Garcias, Xavier; Saa, Jose M. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 328 - 334]