Syntheses of 5-nitro-2-furyl-and 5-nitro-2-thienylacetonitriles

D Végh, J Kováč, M Dandárová

Index: Vegh, Daniel; Kovac, Jaroslav; Dandarova, Miloslava Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 1 p. 114 - 117

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Abstract

The synthesis of nitrofuryl- and nitrothienylacetic acid derivatives was followed in the context of synthetic problems of antibacterial ethylene derivatives with hetero- cyclic residuesl. The acetonitriles substituted with residues of nitro five-membered heterocycles are described only exceptionaIly2. The attempts at syntheses of aceto- nitriles I from easily available furfury13 -5 and theny16.7 dreivatives III, IVfaileds- ll• ... 02N-Z}..CH2"X Z I, X = CN 11. X = H III, X = ...