This study has demonstrated the possibility of S-Cco transannular interaction in medium-ring thiaketones by the ex-amination of the properties of a representative compound, 1- thiacyclooctan-5-one (I). The existence of interacted as well as non-interacted conformations of the ring in solution was demonstrated by a study of its infrared spectrum in the 6 p region, while the conformational equilibrium was studied as a function of solvent polarity in a ...
