Tetrahedron letters

Synthesis of selenocystine derivatives from cystine by applying the transformation reaction from disulfides to diselenides

…, M Miyamoto, A Sugiyama, Y Kohara, N Isozumi

Index: Iwaoka, Michio; Haraki, Chie; Ooka, Ryuta; Miyamoto, Masahiro; Sugiyama, Ai; Kohara, Yumiko; Isozumi, Noriyoshi Tetrahedron Letters, 2006 , vol. 47, # 23 p. 3861 - 3863

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Citation Number: 16

Abstract

A stepwise conversion of a disulfide (SS) to a diselenide (SeSe) bond through the corresponding iodide intermediate was implemented and was applied to the synthesis of selenocystamine and l-selenocystine derivatives from cystamine and l-cystine, respectively, in moderate yields.