Large??scale preparation and labelling reactions of deuterated silanes

…, M Rubio, AC Esqueda, E Carmona

Index: Campos, Jesus; Rubio, Miguel; Esqueda, Ana C.; Carmona, Ernesto Journal of Labelled Compounds and Radiopharmaceuticals, 2012 , vol. 55, # 1 p. 29 - 38

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Citation Number: 8

Abstract

A catalytic synthesis of deuterated silanes SiEt3D, SiMe2PhD and SiPh2D2 is reported that allows their facile generation in a 3–4g scale, utilizing D2 (0.5 bar) as the hydrogen isotope source and low catalyst loadings (0.01 mol%). The catalyst precursor is the rhodium (III) complex 1, which contains a (h5-C5Me5) Rh cation stabilized by coordination to a cyclometallated phoshine PMeXyl2 (Xyl= 2, 6-C6H3Me2). The same complex is also an ...