Tetrahedron letters

Hydrophosphination of α, β-unsaturated esters by primary phosphine-boranes; a useful entry to symmetrical and unsymmetrical phosphine-boranes

K Bourumeau, AC Gaumont, JM Denis

Index: Bourumeau, Karine; Gaumont, Annie-Claude; Denis, Jean-Marc Tetrahedron Letters, 1997 , vol. 38, # 11 p. 1923 - 1926

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Citation Number: 34

Abstract

The reactivity of primary phosphine-boranes RPH2· BH3 (R= Ph and Me) towards CH2 CHCO2Me and CH2 CHP (O)(OMe) 2 is discussed. Hydrophosphination is the major process. The presence of the free phosphine (0–20%) in the crude media indicates that a competitive hydroboration reaction also occurs. The P H addition was found to be controllable to give, in reasonable yields, either the mono or the bis-adducts. All the ...