Intramolecular N–H insertion of α-diazocarbonyls catalyzed by Cu (acac) 2: An efficient route to derivatives of 3-oxoazetidines, 3-oxopyrrolidines and 3-oxopiperidines

J Wang, Y Hou, P Wu

Index: Wang, Jianbo; Hou, Yihua; Wu, Peng Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 16 p. 2277 - 2280

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Citation Number: 33

Abstract

Cu (acac) 2 was found to be an efficient catalyst for the intramolecular N–H insertion by carbenoids. The competitive intramolecular C–H insertion by carbenoids is not a problem in the diazo decomposition reaction with Cu (acac) 2 as catalyst. The reaction provided derivatives of 3-oxoazetidine, 3-oxopyrrolidine and 3-oxopiperidine in moderate to good yields.