e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis and antiviral activity of novel erythrofuranosyl imidazo [1, 2-a] pyridine C-nucleosides constructed via palladium coupling of iodoimidazo [1, 2-a] pyridines …
KS Gudmundsson, JD Williams, JC Drach…
Index: Gudmundsson, Kristjan S.; Tidwell, Jeffrey; Lippa, Nicole; Koszalka, George W.; van Draanen, Nanine; Ptak, Roger G.; Drach, John C.; Townsend, Leroy B. Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2464 - 2472
2, 5, 6-Trichloro-1-(β-d-ribofuranosyl) benzimidazole (TCRB) and certain analogues have shown significant activity against human cytomegalovirus. The metabolic instability of the glycosidic linkage in TCRB prompted us to synthesize the structurally similar imidazo [1, 2-a] pyridine erythrofuranosyl C-nucleosides. As an approach to the synthesis of polychlorinated imidazo [1, 2-a] pyridine C-3-erythrofuranosides, a palladium-based methodology for ...
