Journal of Medicinal Chemistry

3-Phenylcyclobutylamine

A Burger, R Bennett

Index: Burger,A.; Bennett,R. Journal of Medicinal and Pharmaceutical Chemistry, 1960 , vol. 2, p. 687 - 691

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Citation Number: 9

Abstract

The observation that 2-phenylcyclopropylaminel (tranylcypromine) is a potent2 and selectiveS inhibitor of monoamine oxidase led us to experiments directed towards the synthesis of homologous alicyclic amines for comparative biological testing. We are reporting the synthesis of 3-phenylcyclobutylamine, as well as a few reactions of phenylcyclobutane derivatives prepared in this connection.

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