e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Synthesis and Structure of Di [methoxy (ethoxy) carbonylamino-1H-benzimidazol-5-yl] Ethers

…, GV Kiseleva, NA Sapozhnikova, TP Vorob'eva…

Index: Pilyugin; Sapozhnikov; Kiseleva; Sapozhnikova; Vorob'eva; Klimakova Russian Journal of General Chemistry, 2005 , vol. 75, # 10 p. 1509 - 1513

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Citation Number: 4

Abstract

Abstract A procedure was developed for preparing di [methoxy (ethoxy) carbonylamino-1 H- benzimidazol-5-yl] ethers by the reaction of methyl or ethyl chloroformate with sodium cyanamide, followed by the reaction of the resulting methyl or ethyl cyanocarbamate with 4- (3, 4-diaminophenoxy)-1, 2-phenylenediamine in acidic solution.

4-Chloronitrobenzene Structure

4-Chloronitrobenzene

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

4-Acetamidophenol Structure

4-Acetamidophenol

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

Sodium 4-nitrophenoxide Structure

Sodium 4-nitrop...

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

Ethanoic anhydride Structure

Ethanoic anhydride

~99%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

4-nitrophenyl 4'-acetamidophenyl ether Structure

4-nitrophenyl 4...

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

4-(4-Nitrophenoxy)aniline Structure

4-(4-Nitropheno...

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

Na(OC6H4-p-NH2) Structure

Na(OC6H4-p-NH2)

~%

Acetamide,N,N'-(oxydi-4,1-phenylene)bis- (9CI) Structure

Acetamide,N,N'-...

4-nitrophenyl 4'-acetamidophenyl ether Structure

4-nitrophenyl 4...

~77%

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

4-Chloronitrobenzene Structure

4-Chloronitrobenzene

~%

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

4-(4-Nitrophenoxy)aniline Structure

4-(4-Nitropheno...

~%

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

Na(OC6H4-p-NH2) Structure

Na(OC6H4-p-NH2)

~%

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

4-Chloronitrobenzene Structure

4-Chloronitrobenzene

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

4-Acetamidophenol Structure

4-Acetamidophenol

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

Sodium 4-nitrophenoxide Structure

Sodium 4-nitrop...

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

4-nitrophenyl 4'-acetamidophenyl ether Structure

4-nitrophenyl 4...

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

4-(4-Nitrophenoxy)aniline Structure

4-(4-Nitropheno...

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

Na(OC6H4-p-NH2) Structure

Na(OC6H4-p-NH2)

~%

Acetamide,N,N'-[oxybis(2-nitro-4,1-phenylene)]bis- (9CI) Structure

Acetamide,N,N'-...

oxybis[4-nitrobenzene] Structure

oxybis[4-nitrob...

~92%

4,4'-Oxydianiline Structure

4,4'-Oxydianiline

Na(OC6H4-p-NH2) Structure

Na(OC6H4-p-NH2)

4-Chloronitrobenzene Structure

4-Chloronitrobenzene

~82%

4-(4-Nitrophenoxy)aniline Structure

4-(4-Nitropheno...

4-Chloronitrobenzene Structure

4-Chloronitrobenzene

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

Acetamide,N-[4-(4-aminophenoxy)phenyl]- Structure

Acetamide,N-[4-...

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

4-nitrophenyl 4'-acetamidophenyl ether Structure

4-nitrophenyl 4...

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

4-Acetamidophenol Structure

4-Acetamidophenol

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

4-(4-Nitrophenoxy)aniline Structure

4-(4-Nitropheno...

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

Na(OC6H4-p-NH2) Structure

Na(OC6H4-p-NH2)

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

Sodium 4-nitrophenoxide Structure

Sodium 4-nitrop...

~%

3,3',4,4'-Tetraaminodiphenyl Ether Structure

3,3',4,4'-Tetra...

Design of novel bis-benzimidazole derivatives as DNA minor g...

[Wang, Xiu-Jun; Yang, Ming-Li; Zhang, Lan-Ping; Yao, Tong; Chen, Cheng; Mao, Lian-Gang; Wang, Yin; Wu, Jie Chinese Chemical Letters, 2014 , vol. 25, # 4 p. 589 - 592]