Journal of the American Chemical Society

Antitubercular Studies. I. N-Diphenylmethyl-4-alkylpiperidines1, 2

P Truitt, WJ Middleton

Index: Truitt; Middleton Journal of the American Chemical Society, 1951 , vol. 73, p. 5669

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Citation Number: 5

Abstract

The preparation of a number of N-diphenylmethyl-4-alkylpiperidines and N-(9-fluorenyl)-4- alkylpiperidines has been undertaken in order to study the correlation of antitubercular properties and the nature of the 4-alkylpiperidine moiety. These compounds are structurally related to other physiologically active diphenylmethyl derivatives, such as N, N-diethylamin~ diphenylmethane.~ According to a theory advanced by Burger, Graef and Bailey, 4 the ...