Journal of Heterocyclic Chemistry

Reactions of α, β??unsaturated ketones with cyanoacetamide

FH Al??Hajjar, AA Jarrar

Index: Al-Hajjar, Farouk H.; Jarrar, Adil A. Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1521 - 1525

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Citation Number: 17

Abstract

Abstract 3-Aryl-1-phenyl-2-propen-1-ones Ia-f and aroylphenylacetylenes Va-d reacted under reflux for 3 hours with cyanoacetamide in the presence of sodium ethoxide to give the corresponding 4-aryl-3-cyano-6-phenyl-2-(1H) pyridones VI. However, when ketones Ia-e were refluxed with cyanoacetamide for one hour in the presence of sodium ethoxide or piperidine, they gave the corresponding 4-aryl-3-cyano-3, 4-dihydro-6-phenyl-2-(1H) ...