Methyl fluorosulphonyldifluoroacetate; a new trifluoromethylating agent

QY Chen, SW Wu

Index: Chen, Qing-Yun; Wu, Sheng-Wen Journal of the Chemical Society, Chemical Communications, 1989 , # 11 p. 705 - 706

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Citation Number: 119

Abstract

Methyl fluorosulphonyldifluoroacetate, in the presence of copper(1) iodide, is used as the source of trifluoromethyl group which replaces the halogen in aryl, alkenyl, and alkyl halides. ... Recently, considerable attention has been devoted to finding novel methods for introducing the trifluoromethyl group into organic compounds because of increasing demands in medi- cine and biochemistry.' During the course of our investigation into difluorocarbene chemistry2 ...