Organic letters

Magnesium nitride as a convenient source of ammonia: Preparation of primary amides

GE Veitch, KL Bridgwood, SV Ley

Index: Veitch, Gemma E.; Bridgwood, Katy L.; Ley, Steven V. Organic Letters, 2008 , vol. 10, # 16 p. 3623 - 3625

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Citation Number: 47

Abstract

The use of magnesium nitride (Mg3N2) as a convenient source of ammonia has been explored for the direct transformation of esters to primary amides. Methyl, ethyl, isopropyl, and tert-butyl esters are converted to the corresponding carboxamides in good yields (75− 99%).