Tetrahedron Letters

Synthesis of benzofuran-2-one derivatives by copper (I)-promoted coupling reactions of o-bromophenol with active methylene compounds

J Setsune, K Matsukawa, T Kitao

Index: Setsune, Jun-ichiro; Matsukawa, Kimihiro; Kitao, Teijiro Tetrahedron Letters, 1982 , vol. 23, # 6 p. 663 - 666

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Citation Number: 27

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Treatment of o-bromophenoxide anion with sodium salts of active methylene compounds in the presence of copper(I) bromide in dioxane afforded benzofuran-2-one derivatives. The phenoxide group of o- and p-bromophenol activates the coupling reaction. ... Bp 180°C/7 mmHg; IR ...