Chemistry–A European Journal

β??Siloxy?螃窿?haloketones through Highly Diastereoselective Single and Double Mukaiyama Aldol Reactions

J Saadi, H Yamamoto

Index: Saadi, Jakub; Yamamoto, Hisashi Chemistry - A European Journal, 2013 , vol. 19, # 12 p. 3842 - 3845

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Citation Number: 9

Abstract

Halogens, in particular, fluorine and chlorine play a pivotal role in modern medicinal chemistry due to their strong impact on the biological properties of organic molecules.[1] In nature, organohalogens are mainly chlorine compounds of marine origin, and many of them exhibit potent antiproliferative or antibiotic properties.[2] Recently, synthetic chemists turned their attention to chlorosulfolipids [3, 14j] due to their unclear biological role and curious ...