Comparison of Large-Scale Routes to Manufacture Chiral exo-2-Norbornyl Thiourea

…, J Boni, GB Cox, MM Faul, P Franco…

Index: Zhang, Youming; Wei, Taibao; Lu, Jinren Synthetic Communications, 1998 , vol. 28, # 17 p. 3243 - 3248

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Citation Number: 4

Abstract

... The criteria for deciding which approach is most attractive for large-scale applications lie in the overall synthetic strategy. ... Table 2. Resolution screen using chiral acid 5 a. entry, equivalents of 5, CH 3 CN/EtOH, total volume of solvents, 6 (%), DR. 1, 0.5, 4/1, 25, 21, 90/10. ...