e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Kinetics and reactivity of substituted anilines with 2??chloro??5??nitropyridine in dimethyl sulfoxide and dimethyl formamide
…, GM El??Subruiti, FEZM El??Hegazy…
Index: El-Bardan, Ali A.; El-Subruiti, Gehan M.; El-Hegazy, Fatma El-Zahraa M.; Hamed, Ezzat A. International Journal of Chemical Kinetics, 2002 , vol. 34, # 11 p. 645 - 650
Abstract The kinetics of the reaction of substituted anilines with 2-chloro-5-nitropyridine were studied in dimethyl sulfonide (DMSO) and dimethyl formamide (DMF) at different amine concentrations and temperatures in the range 45–60 C. In both solvents the reaction was not a base-catalyzed one. A plot of ΔH# versus ΔS# for the reaction in DMSO and DMF gave good straight lines with isokinetic temperatures 128 C and 105 C, respectively. Good ...