Reaction of 5-nitrosobarbituric acids with thiosemicarbazide

AA Yavolovskii, IM Rakipov, GL Kamalov

Index: Yavolovskii; Rakipov; Kamalov Russian Journal of General Chemistry, 2011 , vol. 81, # 2 p. 447 - 448

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Abstract

Thiosemicarbazones are of interest primarily as ligands for the transition metals coordination [1]. The thiosemicarbazone complexes studied to date have shown a wide spectrum of biological activity: fungicidal, antibacterial, antiviral, and anticancer action [1–9]. The thiosemicarbazones of the pyrimidine series obtained from pyrimidine-2, 4, 5, 6-1H, 3H- tetraone (alloxan) have been poorly studied [10–12]. A major shortcoming of the synthesis ...