Synthesis of Potential Anti-cancer Agents. II. Purine Antagonists from 2-Methylhypoxanthine-8-thiol1

RC ELDERFIELD, RAJN PRASAD

Index: Elderfield; Prasad Journal of Organic Chemistry, 1959 , vol. 24, p. 1410,1413

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Citation Number: 7

Abstract

2-Methylhypoxanthine-% thiol has been condensed with chloroacetic and p-chloropropionic acids to give the corresponding thioacetic and thiopropionic acids which on cyclization gave 4hydroxy-2-methyl-6, 7-dihydrothiazolo-[2.3-f] purine-6-one and 4hydroxy-2-methyl-6, 7-